Between the 1990s and 2010s, society became much more aware of environmental issues, including the ozone layer and climate change. The leakage of refrigerants has been found to contribute to ozone layer damage and unhealthy HFC levels. Because of such issues, there has been a greater drive to develop more environmentally friendly refrigerant options and find new ways to minimize refrigerant leakage.
Advanced EMC Technologies Blog
Probably the most important question to ask about a polymer seal application is the PV value involved.